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Conclusion Our study demonstrated that high expression of S1PR1 contributed to the proliferation and survival of ESCC cells via activating STAT3 signaling pathway. Compare & Order S1PR1 plasmids, CDNA clones, ORF clones and more genomics products. Wide variety of Top suppliers High-quality customer support. 2021-03-22 · Briefly, expression changes include the S1PR1 gene, interleukins, CXLs, the Platelet Activating Factor Receptor (PTAFR) gene 89, and other proteins associated with the interaction of the tumor Human Gene S1PR1 (uc001dud.2) Description and Page Index Description: Homo sapiens sphingosine-1-phosphate receptor 1 (S1PR1), mRNA. RefSeq Summary (NM_001400): The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. S1PR1 is a G-protein-coupled receptor which binds the bioactive signaling molecule sphingosine 1-phosphate (S1P). S1PR1 belon Sphingosine-1-phosphate receptor 1 (S1P receptor 1 or S1P1), also known as endothelial differentiation gene 1 (EDG1) is a protein that in humans is encoded by the S1PR1 gene.
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Sphingosine-1-phosphate - Wikipedia The molecular biology of phospho-fingolimod is thought to lie in its activity at one of the five sphingosine-1-phosphate receptors, S1PR1. Gene information about ENSG00000170989 / S1PR1 - sphingosine-1-phosphate receptor 1 DGIdb, The Drug Gene Interaction Database, is a research resource that can be used to search candidate genes or drugs against the known and potentially druggable genome. Search Search Interactions Search Categories Predicted to localize to cytoplasm and intrinsic component of plasma membrane. Is expressed in several structures, including cardiovascular system; fin bud; nervous system; neural tube; and pleuroperitoneal region. Orthologous to human S1PR1 (sphingosine-1-phosphate receptor 1).
The S1PR1 gene was mapped to river buffalo chromosome 6 using a radiation hybrid panel (Stafuzza et al., 2007).
"ProbeSetID" "Gene.Symbol" "U3002" "U3004" "U3005
doi: 10.1038/nsmb.3014. Epub 2015 Apr 20.
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It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be Edg1 eGFP/eGFP knock-in mice have an EGFP gene inserted downstream of the coding region of the sphingosine-1-phosphate receptor 1 (S1pr1, also known as S1P 1) gene. Edg1 encodes a G-protein-coupled receptor that binds to sphingosine-1-phosphate with high affinity and high specificity. It is essential for vascular development and integrity, and modulates both lymphocyte development and The following S1pr1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S1pr1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. The S1PR1 gene was mapped to river buffalo chromosome 6 using a radiation hybrid panel (Stafuzza et al., 2007).
G-protein coupled receptor for the bioactive lysosphingolipid sphingosine 1-phosphate (S1P) that seems to be coupled to the G (i) subclass of heteromeric G proteins. Signaling leads to the activation of RAC1, SRC, PTK2/FAK1 and MAP kinases. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei.
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The following S1PR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the S1PR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. S1PR1 is crucial for lymphocyte secondary lymphoid organ retention for both T lymphocytes and B lymphocytes.
Showing subcellular location of S1PR1 (CD363, D1S3362, edg-1, EDG1).
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. S1PR1 adalah GReseptor terhubung-protein G yang mengikat sinyal molekul bioaktif sphingosine 1-fosfat (S1 View primary data." is shown for genes analyzed with a knowledge-based approach where available RNA-seq and gene/protein characterization data has been 18 Jan 2019 and the expression of sphingosine 1-phosphate receptor 1 (S1P1, encoded by the S1PR1 gene) in T cells inhibits the generation of Tregs but 23 Feb 2016 We used an inducible mouse model with a temporally disrupted sphingosine-1- phosphate receptor-1 (S1PR1) gene specifically in endogenous HUGO Gene Nomenclature Committee (HGNC) gene group report for Sphingosine 1-phosphate receptors, containing 5 genes within the group.